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Tumor microenvironment influences cancer

Scientists at the Cleveland Clinic Foundation in Ohio report that genetic changes in a tumor’s microenvironment—tissue surrounding cancer—might influence tumor grade and likelihood of lymph node metastasis. Such variations in microenvironment might help explain why cancers are so clinically diverse and could help researchers optimize treatments. (Journal of the American Medical Association, May 16)

Gemzar for early-stage patients

Gemzar (gemcitabine HCl), a chemotherapy drug currently approved for postsurgical treatment of metastatic breast cancer in combination with Taxol (paclitaxel), is showing promise for treating earlier stages of breast cancer too. In one phase 2 study evaluating the addition of Gemzar to paclitaxel, invasive tumors were absent in almost 37 percent of stage II and III patients, say researchers at the Hospital Médico Quirúrgico Ciudad de Jaén in Spain. (June 2 annual meeting of ASCO—the American Society of Clinical Oncology)

Ginseng combats fatigue

Ginseng, an herbal root traditionally used to boost energy, has potential as an antifatigue therapy for cancer patients, say researchers at the Mayo Clinic in Rochester, MN. Patients who took ginseng supplements for eight weeks reported improved energy, more vitality, and increased mental, physical, spiritual and emotional well-being. However, researchers aren’t recommending ginseng to cancer patients just yet, as studies are still ongoing and supermarket supplements vary in quality. (ASCO)

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